Clinicopathological characteristics, molecular landscape, and biomarker landscape for predicting the efficacy of PD-1/PD-L1 inhibitors in Chinese population with mismatch repair deficient urothelial carcinoma: a real-world study

Clinicopathological characteristics, molecular landscape, and biomarker landscape for predicting the efficacy of PD-1/PD-L1 inhibitors in Chinese population with mismatch repair deficient urothelial carcinoma: a real-world study

Urothelial carcinoma (UC) with deficient mismatch repair (dMMR) is a specific subtype of UC characterized by the loss of mismatch repair (MMR) proteins and its association with Lynch syndrome (LS). However, comprehensive real-world data on the incidence, clinicopathological characteristics, molecula...

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Bibliographic Details
Main Authors: Yu-Ting Ma, Fang Hua, Xiu-Ming Zhong, Ying-Jie Xue, Jia Li, Yi-Cong Nie, Xue-Dong Zhang, Ji-Wei Ma, Cun-Hu Lin, Hao-Zhuang Zhang, Wei He, Dan Sha, Miao-Qing Zhao, Zhi-Gang Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
urothelial carcinoma
mismatch repair
Lynch syndrome
PD-1/PD-L1
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1269097/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1269097/full

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