A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets

A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets

Despite major successes with inhibitory receptor blockade in cancer, the identification of novel inhibitory receptors as putative drug targets is needed due to lack of durable responses, therapy resistance, and side effects. Most inhibitory receptors signal via immunoreceptor tyrosine-based inhibito...

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Bibliographic Details
Main Authors: Akashdip Singh, Alberto Miranda Bedate, Helen J von Richthofen, Saskia V Vijver, Michiel van der Vlist, Raphael Kuhn, Alexander Yermanos, Jürgen J Kuball, Can Kesmir, M Ines Pascoal Ramos, Linde Meyaard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-10-01
Series:eLife
Subjects:
bioinformatics
pipeline
cancer immunology
Online Access:https://elifesciences.org/articles/92870

Internet

https://elifesciences.org/articles/92870

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