Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies
Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and severely limits brain penetration of systemically administered drugs, resulting in ineffective drug therapy of brain diseases. However, during the onset and progression of brain diseases, BBB alterations evolve...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-08-01
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| Series: | Acta Pharmaceutica Sinica B |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383520308522 |