Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus

Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus

The genetic basis of systemic lupus erythematosus is not completely understood. Here, the authors perform multi-ancestry and multi-trait meta-analyses to identify 16 novel genetic loci and demonstrate the utility of polygenic risk score in clinical risk prediction when used with conventional lab tes...

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Bibliographic Details
Main Authors: Chachrit Khunsriraksakul, Qinmengge Li, Havell Markus, Matthew T. Patrick, Renan Sauteraud, Daniel McGuire, Xingyan Wang, Chen Wang, Lida Wang, Siyuan Chen, Ganesh Shenoy, Bingshan Li, Xue Zhong, Nancy J. Olsen, Laura Carrel, Lam C. Tsoi, Bibo Jiang, Dajiang J. Liu
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36306-5

Internet

https://doi.org/10.1038/s41467-023-36306-5

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