Prevalence of alleles encoding defective lipoprotein lipase in hypertriglyceridemic patients of French Canadian descent
It has previously been estimated that due to genetic “founder effects,” 97% of lipoprotein lipase (LPL) gene alleles conferring type I hyperlipoproteinemia (HLP) in French Canadians encode one of the following mutant LPL forms: Gly188–>Glu, Pro207–>Leu, or Asp250–>Asn. Although the genetic...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1995-01-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520397601 |