A 3D In Vivo Model for Studying Human Renal Cystic Tissue and Mouse Kidney Slices

A 3D In Vivo Model for Studying Human Renal Cystic Tissue and Mouse Kidney Slices

(1) Background: Autosomal dominant polycystic kidney disease (ADPKD) is a frequent monogenic disorder that leads to progressive renal cyst growth and renal failure. Strategies to inhibit cyst growth in non-human cyst models have often failed in clinical trials. There is a significant need for models...

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Bibliographic Details
Main Authors: Eva-Marie Bichlmayer, Lina Mahl, Leo Hesse, Eric Pion, Victoria Haller, Andreas Moehwald, Christina Hackl, Jens M. Werner, Hans J. Schlitt, Siegfried Schwarz, Philipp Kainz, Christoph Brochhausen, Christian Groeger, Felix Steger, Oliver Kölbl, Christoph Daniel, Kerstin Amann, Andre Kraus, Björn Buchholz, Thiha Aung, Silke Haerteis
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
human renal cystic tissue
ADPKD
chorioallantoic membrane (CAM) model
mouse kidney slices
3D in vivo model
polycystic kidney disease
Online Access:https://www.mdpi.com/2073-4409/11/15/2269

Internet

https://www.mdpi.com/2073-4409/11/15/2269

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