Exosomal miR-186 derived from BMSCs promote osteogenesis through hippo signaling pathway in postmenopausal osteoporosis

Exosomal miR-186 derived from BMSCs promote osteogenesis through hippo signaling pathway in postmenopausal osteoporosis

Abstract Background Postmenopausal osteoporosis (PMO) that results from estrogen withdrawal is the most common primary osteoporosis among older women. However, little is known about the mechanism of PMO, and effective treatment of PMO is limited. Methods We used real-time polymerase chain reaction (...

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Bibliographic Details
Main Authors: Lu Li, Xin Zhou, Jun-tao Zhang, Ai-feng Liu, Chao Zhang, Jin-chang Han, Xiao-qing Zhang, Si Wu, Xiao-yu Zhang, Fu-quan Lv
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Postmenopausal osteoporosis
Exosomes
miRNA
Osteogenesis
Online Access:https://doi.org/10.1186/s13018-020-02160-0

Internet

https://doi.org/10.1186/s13018-020-02160-0

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