Unlocking the potential of dimethyl fumarate: enhancing oncolytic HSV-1 efficacy for wider cancer applications

Unlocking the potential of dimethyl fumarate: enhancing oncolytic HSV-1 efficacy for wider cancer applications

Immunotherapy and specifically oncolytic virotherapy has emerged as a promising option for cancer patients, with oncolytic herpes simplex virus-1 (oHSV-1) expressing granulocyte macrophage colony stimulating factor being the first OV to be approved by the FDA for treatment of melanoma. However, not...

Full description

Bibliographic Details
Main Authors: Akram Alwithenani, Zaid Taha, Max Thomson, Andrew Chen, Boaz Wong, Rozanne Arulanandam, Jean-Simon Diallo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
HSV-1
DMF
cancer
cancer therapeutics
human specimens
fumarate esters
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1332929/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1332929/full

Similar Items