IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells.

Inflammation is a highly coordinated host response to infection, injury, or cell stress. In most instances, the inflammatory response is pro-survival and is aimed at restoring physiological tissue homeostasis and eliminating invading pathogens, although exuberant inflammation can lead to tissue dama...

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Bibliographic Details
Main Authors: Nelson C Di Paolo, Lisa K Baldwin, Eric E Irons, Thalia Papayannopoulou, Stephen Tomlinson, Dmitry M Shayakhmetov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24651866/pdf/?tool=EBI