Loss of RNA binding protein HuD facilitates the production of the senescence-associated secretory phenotype

Abstract HuD, an RNA binding protein, plays a role in the regulation of gene expression in certain types of cells, including neuronal cells and pancreatic β-cells, via RNA metabolism. Its aberrant expression is associated with the pathogenesis of several human diseases. To explore HuD-mediated gene...

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Bibliographic Details
Main Authors: Seungyeon Ryu, Myeongwoo Jung, Chongtae Kim, Hoin Kang, Sukyoung Han, Seongho Cha, Seung Min Jeong, Eun Kyung Lee
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04792-y