Keratoconus: A biomechanical perspective on loss of corneal stiffness

Keratoconus: A biomechanical perspective on loss of corneal stiffness

Keratoconus (KC) is progressive disease of corneal thinning, steepening and collagen degradation. Biomechanics of the cornea is maintained by the intricate collagen network, which is responsible for its unique shape and function. With the disruption of this collagen network, the cornea loses its sha...

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Bibliographic Details
Main Authors: Abhijit Sinha Roy, Rohit Shetty, Mathew Kurian Kummelil
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Epidemiology
keratoconus
prevalence
Disease pathogenesis
genetic heterogeneity
genetics and genomics
genome-wide association study
genomic loci
linkage mapping
molecular mechanisms
whole exome-genome sequencing
Deregulation
ectasia
gene expression
mass spectroscopy
proteomics
signaling pathways
Cornea
crosslinking
modulus
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=8;spage=392;epage=393;aulast=Roy

Internet

http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=8;spage=392;epage=393;aulast=Roy

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