Pembrolizumab (MK-3475) plus platinum and gemcitabine as first-line treatment of recurrent/metastatic head and neck squamous cell carcinoma (PIPER): a phase 2, multicentre, single-arm protocol study in Malaysia

Pembrolizumab (MK-3475) plus platinum and gemcitabine as first-line treatment of recurrent/metastatic head and neck squamous cell carcinoma (PIPER): a phase 2, multicentre, single-arm protocol study in Malaysia

Introduction Treatment combination of pembrolizumab plus platinum and 5-fluorouracil (PF) has increased the survival of recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). The combination of platinum and gemcitabine (PG) has been shown to be superior to PF in the treatment o...

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Bibliographic Details
Main Authors: Gwo Fuang Ho, Soo Hwang Teo, Abqariyah Yahya, Sok Ching Cheong, Kue Peng Lim, Bawani Selvam, Ibtisam Muhamad Nor, Chih Kiang Tan, Yoke Fui Wong, Annie Wai Yeeng Chai, Wan Zamaniah Wan Ishak
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/12/e076898.full

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https://bmjopen.bmj.com/content/14/12/e076898.full

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