In Vivo Hematopoietic Stem Cell Genome Editing: Perspectives and Limitations

The tremendous evolution of genome-editing tools in the last two decades has provided innovative and effective approaches for gene therapy of congenital and acquired diseases. Zinc-finger nucleases (ZFNs), transcription activator- like effector nucleases (TALENs) and CRISPR-Cas9 have been already ap...

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Bibliographic Details
Main Authors: Nikoletta Psatha, Kiriaki Paschoudi, Anastasia Papadopoulou, Evangelia Yannaki
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/12/2222