Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis

Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis

Macrophages play a dual role in regulating tumor progression. They can either reduce tumor growth by secreting antitumorigenic factors or promote tumor progression by secreting a variety of soluble factors. The purpose of this study was to define the monocyte/macrophage population prevalent in skele...

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Bibliographic Details
Main Authors: J.D. Jones, B.P. Sinder, D. Paige, F.N. Soki, A.J. Koh, S. Thiele, Y. Shiozawa, L.C. Hofbauer, S. Daignault, H. Roca, L.K. McCauley
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558618300903

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http://www.sciencedirect.com/science/article/pii/S1476558618300903

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