Attenuation of cGVHD by C5a/C5aR blockade is associated with increased frequency of Treg
Abstract C5aR signaling plays an important role in the regulation of T cell activation and alloimmune responses in chronic graft-versus-host disease (cGVHD). However, direct evidence of this modulation and the efficacy of C5aR blockade in the treatment of cGVHD have not been demonstrated. We observe...
Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Nature Portfolio
2017-06-01
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Σειρά: | Scientific Reports |
Διαθέσιμο Online: | https://doi.org/10.1038/s41598-017-03700-1 |