Attenuation of cGVHD by C5a/C5aR blockade is associated with increased frequency of Treg

Abstract C5aR signaling plays an important role in the regulation of T cell activation and alloimmune responses in chronic graft-versus-host disease (cGVHD). However, direct evidence of this modulation and the efficacy of C5aR blockade in the treatment of cGVHD have not been demonstrated. We observe...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yulian Wang, Peilong Lai, Xiaomei Chen, Chang He, Xin Huang, Suxia Geng, Chenwei Luo, Suijing Wu, Wei Ling, Liye Zhong, Zesheng Lu, Peng Li, Jianyu Weng, Xin Du
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Portfolio 2017-06-01
Σειρά:Scientific Reports
Διαθέσιμο Online:https://doi.org/10.1038/s41598-017-03700-1