Design and comparative in-vitro and in-vivo evaluation of starch-acrylate graft copolymer based salbutamol sulphate sustained release tablets

Design and comparative in-vitro and in-vivo evaluation of starch-acrylate graft copolymer based salbutamol sulphate sustained release tablets

The present work deals with the development of controlled release tablets of salbutamol sulphate (SS) using graft copolymers of methyl methacrylate (St-g-PMMA and Ast-g-PMMA) on starch and acetylated starch. Formulations were evaluated for physical characteristics like hardness, friability, drug rel...

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Bibliographic Details
Main Authors: Pankaj Kumar, Ashok Laxmanrao Ganure, Bharat Bhushan Subudhi, Shubhanjali Shukla, Pooja Upadhyay
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Salbutamol sulphate
Methyl methacrylate
Graft copolymers
Acetylated starch
Korsmeyer's model
In vitro and in vivo
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087614001007

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http://www.sciencedirect.com/science/article/pii/S1818087614001007

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