Determination of HER2 amplification status on tumour DNA by digital PCR.

Determination of the presence of HER2 amplification by quantitative PCR has been challenging, in part due to chromosomal instability and identification of a robust a reference region. We assessed the potential of digital PCR for highly accurate assessment of DNA concentration with EFTUD2 as chromoso...

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Bibliographic Details
Main Authors: Isaac Garcia-Murillas, Maryou Lambros, Nicholas C Turner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873285?pdf=render