Computer-Based Identification of Potential Druggable Targets in Multidrug-Resistant <i>Acinetobacter baumannii</i>: A Combined In Silico, In Vitro and In Vivo Study

Computer-Based Identification of Potential Druggable Targets in Multidrug-Resistant <i>Acinetobacter baumannii</i>: A Combined In Silico, In Vitro and In Vivo Study

The remarkable rise in antimicrobial resistance is alarming for <i>Acinetobacter baumannii</i>, which necessitates effective strategies for the discovery of promising anti-acinetobacter agents. We used a subtractive proteomics approach to identify unique protein drug targets. Shortlisted...

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Bibliographic Details
Main Authors: Omar H. Badie, Ahmed F. Basyony, Reham Samir
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Microorganisms
Subjects:
<i>Acinetobacter baumannii</i>
multidrug-resistant
subtractive proteomics
drug targets
aspartate 1-decarboxylase
malonic acid
Online Access:https://www.mdpi.com/2076-2607/10/10/1973

Internet

https://www.mdpi.com/2076-2607/10/10/1973

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