Validation of microRNA-199b as A Promising Predictor of Outcome and Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer Patients

Validation of microRNA-199b as A Promising Predictor of Outcome and Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer Patients

The absence of established predictive markers with value to anticipate response to neoadjuvant 5-fluorouracil (5-FU)-based chemoradiotherapy (CRT) represents a current major challenge in locally advanced rectal cancer (LARC). The tumor suppressor microRNA (miR)-199b has been reported to play a key r...

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Bibliographic Details
Main Authors: Ion Cristóbal, Andrea Santos, Jaime Rubio, Cristina Caramés, Sandra Zazo, Marta Sanz-Álvarez, Melani Luque, Juan Madoz-Gúrpide, Federico Rojo, Jesús García-Foncillas
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
MiR-199b
locally advanced rectal cancer
prognosis
pathological response
Online Access:https://www.mdpi.com/2072-6694/13/19/5003

Internet

https://www.mdpi.com/2072-6694/13/19/5003

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