Gut microbiota and metabolic profiles in chronic intermittent hypoxia-induced rats: disease-associated dysbiosis and metabolic disturbances

Gut microbiota and metabolic profiles in chronic intermittent hypoxia-induced rats: disease-associated dysbiosis and metabolic disturbances

AimChronic intermittent hypoxia (CIH) is a key characteristic of obstructive sleep apnea (OSA) syndrome, a chronic respiratory disorder. The mechanisms of CIH-induced metabolic disturbance and histopathological damage remain unclear.MethodsCIH-induced rats underwent daily 8-h CIH, characterized by o...

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Bibliographic Details
Main Authors: Cong Li, Song Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Endocrinology
Subjects:
obstructive sleep apnea
chronic intermittent hypoxia
gut microbiota
metabolomics
cAMP pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1224396/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1224396/full

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