Gut microbiota and metabolic profiles in chronic intermittent hypoxia-induced rats: disease-associated dysbiosis and metabolic disturbances

Gut microbiota and metabolic profiles in chronic intermittent hypoxia-induced rats: disease-associated dysbiosis and metabolic disturbances

AimChronic intermittent hypoxia (CIH) is a key characteristic of obstructive sleep apnea (OSA) syndrome, a chronic respiratory disorder. The mechanisms of CIH-induced metabolic disturbance and histopathological damage remain unclear.MethodsCIH-induced rats underwent daily 8-h CIH, characterized by o...

Full description

Bibliographic Details
Main Authors:	Cong Li, Song Shi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Series:	Frontiers in Endocrinology
Subjects:	obstructive sleep apnea chronic intermittent hypoxia gut microbiota metabolomics cAMP pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1224396/full

Similar Items

Associations of Intermittent Hypoxia Burden with Gut Microbiota Dysbiosis in Adult Patients with Obstructive Sleep Apnea
by: Guo W, et al.
Published: (2024-09-01)

Hydrogen Attenuates Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy by Regulating Iron Metabolism
by: Jixian Song, et al.
Published: (2023-12-01)

Gut microbiota has important roles in the obstructive sleep apnea-induced inflammation and consequent neurocognitive impairment
by: Mingxing Tang, et al.
Published: (2024-12-01)

Ocular Inflammation and Oxidative Stress as a Result of Chronic Intermittent Hypoxia: A Rat Model of Sleep Apnea
by: Nina Donkor, et al.
Published: (2024-07-01)

Identification of key genes in chronic intermittent hypoxia-induced lung cancer progression based on transcriptome sequencing
by: Li-Da Chen, et al.
Published: (2024-01-01)

Recent progresses in gut microbiome mediates obstructive sleep apnea‐induced cardiovascular diseases
by: Xiaotong Zhang, et al.
Published: (2024-04-01)

Gestational intermittent hypoxia reduces mandibular growth with decreased Sox9 expression and increased Hif1a expression in male offspring rats
by: Takumi Suzuki, et al.
Published: (2024-06-01)

CircRNA expression profiles and functional analysis in a mouse model of chronic intermittent hypoxia-induced renal injury: new insight into pathogenesis
by: Qingshi Chen, et al.
Published: (2023-02-01)

Time-dependent inflammatory factor production and NFκB activation in a rodent model of intermittent hypoxia
by: S Li, et al.
Published: (2011-11-01)

Ferrostatin-1 Reversed Chronic Intermittent Hypoxia-Induced Ferroptosis in Aortic Endothelial Cells via Reprogramming Mitochondrial Function
by: Chen J, et al.
Published: (2024-04-01)

Intermittent hypoxia by obstructive sleep apnea is significantly associated with electro-anatomical remodeling of the left atrium preceding structural remodeling in patients with atrial fibrillation
by: Yasuyuki Takada, et al.
Published: (2024-10-01)

Reoxygenation Mitigates Intermittent Hypoxia-Induced Systemic Inflammation and Gut Microbiota Dysbiosis in High-Fat Diet-Induced Obese Rats
by: Dong M, et al.
Published: (2024-05-01)

Progress in animal model research on obstructive sleep apnea
by: SHEN Yubin, et al.
Published: (2024-04-01)

Acetylome Analyses Provide New Insights into the Effect of Chronic Intermittent Hypoxia on Hypothalamus-Dependent Endocrine Metabolism Impairment
by: Yaru Kong, et al.
Published: (2024-07-01)

The Effects of Volatile Anesthetics on Renal Sympathetic and Phrenic Nerve Activity during Acute Intermittent Hypoxia in Rats
by: Josip Krnić, et al.
Published: (2024-04-01)

Impact of Chronic Intermittent Hypoxia on Cognitive Function and Hippocampal Neurons in Mice: A Study of Inflammatory and Oxidative Stress Pathways
by: Zhang K, et al.
Published: (2024-12-01)

Possible Molecular Mechanisms of Hypertension Induced by Sleep Apnea Syndrome/Intermittent Hypoxia
by: Yoshinori Takeda, et al.
Published: (2024-01-01)

Gestational Intermittent Hypoxia Enhances Mammary Stem Cells and Alters Tumor Phenotype in Adult Female Offspring
by: Jaitri Joshi, et al.
Published: (2024-01-01)

Identification of novel biomarkers in obstructive sleep apnea via integrated bioinformatics analysis and experimental validation
by: Kai Zhang, et al.
Published: (2023-12-01)

Acute intermittent hypoxia: Enhancing motoneuronal output or not?
by: Simon C. Gandevia, et al.
Published: (2024-09-01)

Pyroptosis: An Accomplice in the Induction of Multisystem Complications Triggered by Obstructive Sleep Apnea
by: Jingwen Han, et al.
Published: (2024-10-01)

Altitude and Breathing during Sleep in Healthy Persons and Sleep Disordered Patients: A Systematic Review
by: Stephanie Rojas-Córdova, et al.
Published: (2023-03-01)

Obstructive sleep apnea and amyloid-β42 in adolescents: The results of a pilot study
by: O. N. Berdina, et al.
Published: (2022-07-01)

A review of obstructive sleep apnea and lung cancer: epidemiology, pathogenesis, and therapeutic options
by: Fang Yuan, et al.
Published: (2024-03-01)

Shedding light on neurofilament involvement in cognitive decline in obstructive sleep apnea and its possible role as a biomarker
by: Julia Jaromirska, et al.
Published: (2023-11-01)

Effects of Intermittent and Chronic Hypoxia on Fish Size and Nutrient Metabolism in Tiger Puffer (<i>Takifugu rubripes</i>)
by: Qiang Ma, et al.
Published: (2024-08-01)

Obstructive sleep apnea, intermittent hypoxemia and prothrombotic biomarkers
by: Kunal Deokar, et al.
Published: (2020-10-01)

T cell receptor repertoire as a novel indicator for identification and immune surveillance of patients with severe obstructive sleep apnea
by: Kai Li, et al.
Published: (2023-04-01)

Ferroptosis-related genes are considered as potential targets for CPAP treatment of obstructive sleep apnea
by: Jing Huang, et al.
Published: (2023-12-01)

Intermittent Hypoxia-Induced Cardiomyocyte Death Is Mediated by HIF-1 Dependent MAM Disruption
by: Sophie Moulin, et al.
Published: (2022-07-01)

Danggui-Buxue decoction alleviated vascular senescence in mice exposed to chronic intermittent hypoxia through activating the Nrf2/HO-1 pathway
by: Dongli Li, et al.
Published: (2023-12-01)

Alterations in Gut Microbiota Composition Are Associated with Changes in Emotional Distress in Children with Obstructive Sleep Apnea
by: Chung-Guei Huang, et al.
Published: (2024-12-01)

Risk factors of obstructive sleep apnea syndrome in the developmental age
by: Irena Sionek, et al.
Published: (2024-10-01)

The effect of continuous positive airway pressure therapy on atrial fibrillation in patients with obstructive sleep apnea
by: Jiancheng Hu, et al.
Published: (2025-01-01)

Dual Approach to Depression: The Combined Efficacy of Intermittent Hypoxia and Fluoxetine in Modulating Behavioral and Inflammatory Responses
by: Francini Arboit, et al.
Published: (2024-09-01)

A single sequence of intermittent hypoxia does not alter stretch reflex excitability in able‐bodied individuals
by: Andrew Q. Tan, et al.
Published: (2024-04-01)

Can Galectin-3 Be Used as a Predictor of Obstructive Sleep Apnea Severity: Insights from High-Volume Patient Single Center
by: Milica Brajkovic, et al.
Published: (2025-02-01)

Self-Reported Sleepiness, Fatigue and Risk of Obstructive Sleep Apnea Using the STOP BANG Components: Women’s Perspective
by: Jasmine M, et al.
Published: (2023-11-01)

Clinical Application of the Multicomponent Grading System for Sleep Apnea Classification and Incident Cardiovascular Mortality
by: Jorge Jorquera, et al.
Published: (2023-12-01)

A comprehensive review of obstructive sleep apnea
by: Anna Abbasil, et al.
Published: (2021-06-01)