Implications of NLRP3 Suppression Using Glibenclamide and miR-223 against Colorectal Cancer

Implications of NLRP3 Suppression Using Glibenclamide and miR-223 against Colorectal Cancer

The NLR family pyrin domain containing 3 (NLRP3) promotes the growth of colorectal cancer (CRC). However, the therapeutic effect of NLRP3 inhibition on CRC cell progression is controversial. This study comparatively investigated the therapeutic effect of a pharmacological NLRP3 inhibitor, glibenclam...

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Bibliographic Details
Main Authors: Shaimaa Hamza, Ekaterina E. Garanina, Layaly Shkair, Mohammad Alsaadi, Svetlana F. Khaiboullina, Gulcin Tezcan
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceuticals
Subjects:
NLRP3
inflammasome
glibenclamide
microRNA-223
colorectal cancer
metastasis
Online Access:https://www.mdpi.com/1424-8247/17/3/299

Internet

https://www.mdpi.com/1424-8247/17/3/299

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