Comparison of drug release and mechanical properties of tramadol-hydrochloride matrix tablets prepared with selected hydrophilic polymers

This study investigates using of high molecular weight hydrophilic polymers, hypromellose and hydroxypropylcellulose, for the preparation of sustained release matrix tablets containing high dose, highly soluble drug, tramadol HCl. Proportion of polymer, type of insoluble filler, proportion...

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Bibliographic Details
Main Authors: Nikolić Nenad D., Medarević Đorđe P., Đuriš Jelena D., Vasiljević Dragana D.
Format: Article
Language:English
Published: Association of the Chemical Engineers of Serbia 2015-01-01
Series:Chemical Industry and Chemical Engineering Quarterly
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/1451-9372/2015/1451-93721400040N.pdf