<i>Bacteroides fragilis</i> Toxin Induces Intestinal Epithelial Cell Secretion of Interleukin-8 by the E-Cadherin/β-Catenin/NF-κB Dependent Pathway

Enterotoxigenic <i>Bacteroides fragilis</i> (ETBF) has emerged as a gut microbiome pathogen that can promote colitis associated cancer in humans. ETBF secretes the metalloprotease, <i>B. fragilis</i> toxin (BFT), which can induce ectodomain cleavage of E-cadherin and IL-8 sec...

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Main Authors: Chang-Gun Lee, Soonjae Hwang, Sun-Yeong Gwon, Chanoh Park, Minjeong Jo, Ju-Eun Hong, Ki-Jong Rhee
格式: 文件
语言:English
出版: MDPI AG 2022-03-01
丛编:Biomedicines
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在线阅读:https://www.mdpi.com/2227-9059/10/4/827