CMKLR1 activation ex vivo does not increase proportionally to serum total chemerin in obese humans

Prochemerin is the inactive precursor of the adipokine chemerin. Proteolytic processing is obligatory for the conversion of prochemerin into active chemerin and subsequent regulation of cellular processes via the chemokine-like receptor 1 (CMKLR1). Elevated plasma or serum chemerin concentrations an...

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Bibliographic Details
Main Authors: Jay Toulany, Sebastian D Parlee, Christopher J Sinal, Kathryn Slayter, Shelly McNeil, Kerry B Goralski
Format: Article
Language:English
Published: Bioscientifica 2016-11-01
Series:Endocrine Connections
Subjects:
Online Access:http://www.endocrineconnections.com/content/5/6/70.full