Functional Validation of the Putative Oncogenic Activity of <i>PLAU</i>

Functional Validation of the Putative Oncogenic Activity of <i>PLAU</i>

Plasminogen activator, urokinase (<i>PLAU</i>) is involved in cell migration, proliferation and tissue remodeling. <i>PLAU</i> upregulation is associated with an increase in aggressiveness, metastasis, and invasion of several cancer types, including breast cancer. In patients...

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Bibliographic Details
Main Authors: Federica Sarno, Désirée Goubert, Emilie Logie, Martijn G. S. Rutten, Mihaly Koncz, Christophe Deben, Anita E. Niemarkt, Lucia Altucci, Pernette J. Verschure, Antal Kiss, Wim Vanden Berghe, Marianne G. Rots
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
Epigenetic Editing
CRISPR-dCas9
triple negative breast cancer
<i>PLAU</i>
oncogene
Online Access:https://www.mdpi.com/2227-9059/11/1/102

Internet

https://www.mdpi.com/2227-9059/11/1/102

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