Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia

Modeling pulmonary fibrosis by abnormal expression of telomerase/apoptosis/collagen V in experimental usual interstitial pneumonia

Limitations on tissue proliferation capacity determined by telomerase/apoptosis balance have been implicated in pathogenesis of idiopathic pulmonary fibrosis. In addition, collagen V shows promise as an inductor of apoptosis. We evaluated the quantitative relationship between the telomerase/apoptosi...

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Bibliographic Details
Main Authors: E.R. Parra, M.S. Pincelli, W.R. Teodoro, A.P.P. Velosa, V. Martins, M.P. Rangel, J.V. Barbas-Filho, V.L. Capelozzi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
BHT experimental model
Usual interstitial pneumonia
Alveolar epithelial cell apoptosis
Telomerase activity
Collagen V
Electron microscopy
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000700567&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000700567&lng=en&tlng=en

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