A High-Sodium Diet in Streptozotocin-Induced Diabetic Rats Impairs Endothelium-Derived Hyperpolarizing Factor-Mediated Vasodilation

A High-Sodium Diet in Streptozotocin-Induced Diabetic Rats Impairs Endothelium-Derived Hyperpolarizing Factor-Mediated Vasodilation

We examined endothelium-derived hyperpolarizing factor (EDHF)-mediated relaxation of mesenteric arteries in high-sodium loaded streptozotocin (STZ)-induced diabetic rats. The study shows that acetylcholine (ACh)-induced, EDHF-mediated relaxation is relatively maintained in STZ-induced diabetic rats,...

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Bibliographic Details
Main Authors: Yasutoshi Hirabara, Mina Araki, Mio Fukuda, Shiori Katafuchi, Kenji Honda, Ryo Saito, Yukio Takano
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319342410

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http://www.sciencedirect.com/science/article/pii/S1347861319342410

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