Dynamic Interplay of Smooth Muscle α-Actin Gene-Regulatory Proteins Reflects the Biological Complexity of Myofibroblast Differentiation

Myofibroblasts (MFBs) are smooth muscle-like cells that provide contractile force required for tissue repair during wound healing. The leading agonist for MFB differentiation is transforming growth factor β1 (TGFβ1) that induces transcription of genes encoding smooth muscle α-actin (SMαA) and inters...

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Bibliographic Details
Main Authors: Seethalakshmi Hariharan, Arthur Roger Strauch
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Biology
Subjects:
Online Access:http://www.mdpi.com/2079-7737/2/2/555