A single-dose live attenuated chimeric vaccine candidate against Zika virus

A single-dose live attenuated chimeric vaccine candidate against Zika virus

Abstract The mosquito-borne Zika virus is an emerging pathogen from the Flavivirus genus for which there are no approved antivirals or vaccines. Using the clinically validated PDK-53 dengue virus vaccine strain as a backbone, we created a chimeric dengue/Zika virus, VacDZ, as a live attenuated vacci...

Full description

Bibliographic Details
Main Authors: Wei-Xin Chin, Regina Ching Hua Lee, Parveen Kaur, Tian Sheng Lew, Thinesshwary Yogarajah, Hao Yuin Kong, Zi-Yun Teo, Cyrill Kafi Salim, Rong-Rong Zhang, Xiao-Feng Li, Sylvie Alonso, Cheng-Feng Qin, Justin Jang Hann Chu
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00282-y

Internet

https://doi.org/10.1038/s41541-021-00282-y

Similar Items