Stem Cell-Based Trophoblast Models to Unravel the Genetic Causes of Human Miscarriages

Miscarriage affects approximately 15% of clinically recognized pregnancies, and 1–3% of couples experience pregnancy loss recurrently. Approximately 50–60% of miscarriages result from chromosomal abnormalities, whereas up to 60% of euploid recurrent abortions harbor variants in candidate genes. The...

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Bibliographic Details
Main Authors: Tatiana V. Nikitina, Igor N. Lebedev
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/12/1923