A Novel Morphine Drinking Model of Opioid Dependence in Rats

A Novel Morphine Drinking Model of Opioid Dependence in Rats

An animal model of voluntary oral morphine consumption would allow for a pre-clinical evaluation of new treatments aimed at reducing opioid intake in humans. However, the main limitation of oral morphine consumption in rodents is its bitter taste, which is strongly aversive. Taste aversion is often...

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Bibliographic Details
Main Authors: Pablo Berríos-Cárcamo, Mauricio Quezada, Daniela Santapau, Paola Morales, Belén Olivares, Carolina Ponce, Alba Ávila, Cristian De Gregorio, Marcelo Ezquer, María Elena Quintanilla, Mario Herrera-Marschitz, Yedy Israel, Fernando Ezquer
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
morphine
opioids
addiction
oral intake
animal model
dependence
Online Access:https://www.mdpi.com/1422-0067/23/7/3874

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https://www.mdpi.com/1422-0067/23/7/3874

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