Cocrystals Enhance Biopharmaceutical and Antimicrobial Properties of Norfloxacin

A solvate cocrystal of the antimicrobial norfloxacin (NFX) was formed by using isonicotinamide (INA) as a coformer with the solvent evaporation technique. The cocrystal formation was confirmed by performing solid-state characterization techniques. We evaluated the dissolution under supersaturated co...

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Bibliographic Details
Main Authors: Samantha Nascimento Gomes, Isabela Fanelli Barreto Biscaia, Diana Schon Lopes, Mariana Mengarda, Fábio Seigi Murakami, Paulo Renato Oliveira, Larissa Sakis Bernardi
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/9/2211