Exosome-sheathed ROS-responsive nanogel to improve targeted therapy in perimenopausal depression

Exosome-sheathed ROS-responsive nanogel to improve targeted therapy in perimenopausal depression

Abstract The development of natural membranes as coatings for nanoparticles to traverse the blood-brain barrier (BBB) presents an effective approach for treating central nervous system (CNS) disorders. In this study, we have designed a nanogel loaded with PACAP and estrogen (E2), sheathed with exoso...

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Bibliographic Details
Main Authors: Yue Hu, Min Zhao, Hui Wang, Yang Guo, Xiaolan Cheng, Tong Zhao, Hanqing Wang, Yafeng Zhang, Yong Ma, Weiwei Tao
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Nanobiotechnology
Subjects:
Exosome
Nanogel
Perimenopausal Depression
PACAP
Estrogen
Online Access:https://doi.org/10.1186/s12951-023-02005-y

Internet

https://doi.org/10.1186/s12951-023-02005-y

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