Co-culture of Murine Neurons Using a Microfluidic Device for The Study of Tau Misfolding Propagation

The deposition of misfolded, aggregated tau protein is a hallmark of several neurodegenerative diseases, collectively termed “tauopathies”. Tau pathology spreads throughout the brain along connected pathways in a prion-like manner. The process of tau pathology propagation across circuits is a focus...

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Bibliographic Details
Main Authors: Grace Hallinan, Dianne Lopez, Mariana Vargas-Caballero, Jonathan West, Katrin Deinhardt
Format: Article
Language:English
Published: Bio-protocol LLC 2020-08-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=3718&type=0