Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation

Machine learning model for anti-cancer drug combinations: Analysis, prediction, and validation

Drug combination therapy is a highly effective approach for enhancing the therapeutic efficacy of anti-cancer drugs and overcoming drug resistance. However, the innumerable possible drug combinations make it impractical to screen all synergistic drug pairs. Moreover, biological insights into synergi...

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Bibliographic Details
Main Authors: Jing-Bo Zhou, Dongyang Tang, Lin He, Shiqi Lin, Josh Haipeng Lei, Heng Sun, Xiaoling Xu, Chu-Xia Deng
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Pharmacological Research
Subjects:
Drug combination therapy
Machine learning
Three-dimensional tumor slice culture
Potential combination biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S104366182300186X

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http://www.sciencedirect.com/science/article/pii/S104366182300186X

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