Comprehensive Statistical and Bioinformatics Analysis in the Deciphering of Putative Mechanisms by Which Lipid-Associated GWAS Loci Contribute to Coronary Artery Disease

Comprehensive Statistical and Bioinformatics Analysis in the Deciphering of Putative Mechanisms by Which Lipid-Associated GWAS Loci Contribute to Coronary Artery Disease

The study was designed to evaluate putative mechanisms by which lipid-associated loci identified by genome-wide association studies (GWAS) are involved in the molecular pathogenesis of coronary artery disease (CAD) using a comprehensive statistical and bioinformatics analysis. A total of 1700 unrela...

Full description

Bibliographic Details
Main Authors: Victor Lazarenko, Mikhail Churilin, Iuliia Azarova, Elena Klyosova, Marina Bykanova, Natalia Ob'edkova, Mikhail Churnosov, Olga Bushueva, Galina Mal, Sergey Povetkin, Stanislav Kononov, Yulia Luneva, Sergey Zhabin, Anna Polonikova, Alina Gavrilenko, Igor Saraev, Maria Solodilova, Alexey Polonikov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomedicines
Subjects:
genome-wide association study
plasma lipids
carotid intima-media thickness
coronary artery disease
disease susceptibility
Online Access:https://www.mdpi.com/2227-9059/10/2/259

Internet

https://www.mdpi.com/2227-9059/10/2/259

Similar Items