Design of a multicomponent peptide-woven nanocomplex for delivery of siRNA.

Design of a multicomponent peptide-woven nanocomplex for delivery of siRNA.

We developed and tested a multicomponent peptide-woven siRNA nanocomplex (PwSN) comprising different peptides designed for efficient cellular targeting, endosomal escape, and release of siRNA. To enhance tumor-specific cellular uptake, we connected an interleukin-4 receptor-targeting peptide (I4R) t...

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Bibliographic Details
Main Authors: Eunsung Jun, Soyoun Kim, Jong-Ho Kim, Kiweon Cha, In-Seop So, Hye-Nam Son, Byung-Heon Lee, Kwangmeyung Kim, Ick Chan Kwon, Sang Yoon Kim, In-San Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118310&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118310&type=printable

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