Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss.
Fitness is a parameter used to quantify how well an organism adapts to its environment; in the present study, fitness is a measure of how well strains of human immunodeficiency virus type 1 (HIV-1) replicate in tissue culture. When HIV-1 develops resistance in vitro or in vivo to antiretroviral drug...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-06-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC1885273?pdf=render |