Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss.

Escape of HIV-1 from a small molecule CCR5 inhibitor is not associated with a fitness loss.

Fitness is a parameter used to quantify how well an organism adapts to its environment; in the present study, fitness is a measure of how well strains of human immunodeficiency virus type 1 (HIV-1) replicate in tissue culture. When HIV-1 develops resistance in vitro or in vivo to antiretroviral drug...

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Bibliographic Details
Main Authors: Cleo G Anastassopoulou, Andre J Marozsan, Alexandre Matet, Amy D Snyder, Eric J Arts, Shawn E Kuhmann, John P Moore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1885273?pdf=render

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