A most wanted list of conserved microbial protein families with no known domains.

The number and proportion of genes with no known function are growing rapidly. To quantify this phenomenon and provide criteria for prioritizing genes for functional characterization, we developed a bioinformatics pipeline that identifies robustly defined protein families with no annotated domains,...

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Bibliographic Details
Main Authors: Stacia K Wyman, Aram Avila-Herrera, Stephen Nayfach, Katherine S Pollard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6192648?pdf=render