Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells

Abstract Background The stem cell-based therapies for intervertebral disc degeneration have been widely studied. However, the mechanisms of mesenchymal stem cells interacting with intervertebral disc cells, such as nucleus pulposus cells (NPCs), remain unknown. Exosomes as a vital paracrine mechanis...

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Bibliographic Details
Main Authors: Kang Lu, Hai-yin Li, Kuang Yang, Jun-long Wu, Xiao-wei Cai, Yue Zhou, Chang-qing Li
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Stem Cell Research & Therapy
Subjects:
Intervertebral disc degeneration
Exosomes
Mesenchymal stem cell
Nucleus pulposus cell
Differentiation
Proliferation
Online Access:http://link.springer.com/article/10.1186/s13287-017-0563-9

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http://link.springer.com/article/10.1186/s13287-017-0563-9

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