Mechanistic Insights into Membrane Protein Clustering Revealed by Visualizing EGFR Secretion

Most plasmalemmal proteins are organized into clusters to modulate various cellular functions. However, the machineries that regulate protein clustering remain largely unclear. Here, with EGFR as an example, we directly and in detail visualized the entire process of EGFR from synthesis to secretion...

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Bibliographic Details
Main Authors: Haijiao Xu, Jinrui Zhang, Yijia Zhou, Guanfang Zhao, Mingjun Cai, Jing Gao, Lina Shao, Yan Shi, Hongru Li, Hongbin Ji, Yikai Zhao, Hongda Wang
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-01-01
Series:Research
Online Access:http://dx.doi.org/10.34133/2022/9835035