Genetic Interactions between the Members of the SMN-Gemins Complex in Drosophila.

The SMN-Gemins complex is composed of Gemins 2-8, Unrip and the survival motor neuron (SMN) protein. Limiting levels of SMN result in the neuromuscular disorder, spinal muscular atrophy (SMA), which is presently untreatable. The most-documented function of the SMN-Gemins complex concerns the assembl...

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Bibliographic Details
Main Authors: Rebecca M Borg, Rémy Bordonne, Neville Vassallo, Ruben J Cauchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4476591?pdf=render