Cytokine competent gut-joint migratory T Cells contribute to inflammation in the joint

Although studies have identified the presence of gut-associated cells in the enthesis of joints affected by spondylarthritis (SpA), a direct link through cellular transit between the gut and joint has yet to be formally demonstrated. Using KikGR transgenic mice to label in situ and track cellular tr...

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Bibliographic Details
Main Authors: Adam R. Lefferts, Eric Norman, David J. Claypool, Uma Kantheti, Kristine A. Kuhn
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.932393/full