Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C− Kupffer Cell Subsets

Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C− Kupffer Cell Subsets

BackgroundLipopolysaccharide (LPS) decreases hepatic CETP (cholesteryl ester transfer protein) expression albeit that the underlying mechanism is disputed. We recently showed that plasma CETP is mainly derived from Kupffer cells (KCs). In this study, we investigated the role of KC subsets in the mec...

Full description

Bibliographic Details
Main Authors: Sam J. L. van der Tuin, Zhuang Li, Jimmy F. P. Berbée, Inge Verkouter, Linda E. Ringnalda, Annette E. Neele, Jan B. van Klinken, Sander S. Rensen, Jingyuan Fu, Menno P. J. de Winther, Albert K. Groen, Patrick C. N. Rensen, Ko Willems van Dijk, Yanan Wang
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
inflammation
lipids and lipoprotein metabolism
liver
macrophage
marker
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.008105

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.117.008105

Similar Items