Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies

Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies

Biomarkers to discriminate the main pathologies underlying frontotemporal lobar degeneration (FTLD-Tau, FTLD-TDP) are lacking. Our previous FTLD cerebrospinal fluid (CSF) proteome study revealed that sex hormone-binding globulin (SHBG) was specifically increased in FTLD-Tau patients. Here we investi...

Full description

Bibliographic Details
Main Authors: Marta del Campo, Yolande A. L. Pijnenburg, Alice Chen-Plotkin, David J. Irwin, Murray Grossman, Harry A. M. Twaalfhoven, William T. Hu, Lieke H. Meeter, John van Swieten, Lisa Vermunt, Frans Martens, Annemieke C. Heijboer, Charlotte E. Teunissen
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomolecules
Subjects:
CSF
biomarkers
FTLD-Tau
FTLD-TDP
Online Access:https://www.mdpi.com/2218-273X/11/10/1484

Internet

https://www.mdpi.com/2218-273X/11/10/1484

Similar Items