β-catenin mediates the effect of GLP-1 receptor agonist on ameliorating hepatic steatosis induced by high fructose diet

β-catenin mediates the effect of GLP-1 receptor agonist on ameliorating hepatic steatosis induced by high fructose diet

The hypoglycemic drug GLP-1 receptor agonist can ameliorate hepatic steatosis but the mechanism is not clear. Intake of high fructose leads to non-alcoholic fatty liver disease by stimulating lipid synthesis, and β-catenin is the key molecule for realizing GLP-1 function in extrahepatic tissues; wit...

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Bibliographic Details
Main Authors: Zhe Gao, Guang-Yao Song, Lu-Ping Ren, Hui-Juan Ma, Bo-Qing Ma, Shu-Chun Chen
Format: Article
Language:English
Published: PAGEPress Publications 2020-09-01
Series:European Journal of Histochemistry
Subjects:
Fructose
hepatic steatosis
GLP-1 receptor agonist
β-catenin
de novo lipogenesis
Online Access:https://ejh.it/index.php/ejh/article/view/3160

Internet

https://ejh.it/index.php/ejh/article/view/3160

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