Tizoxanide as a novel theraputic candidate for osteoarthritis

Osteoarthritis (OA) is a frequently seen degenerative joint disease in the elderly. Its pathogenesis is highly related to the local inflammatory reaction and autophagy. Tizoxanide (Tiz), the main active metabolite of nitazoxanide, has proved its anti-inflammatory properties in several diseases. Howe...

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Bibliographic Details
Main Authors: Bowei Ni, Jiyuan Yan, Wenxiang Cai, Yifan Xiao, Chang Tu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402306680X