mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis

mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis

Ovarian cancer is the second most common cause of gynecological cancer death in women. It is usually diagnosed late and accompanied by peritoneal metastasis. For ovarian cancer with peritoneal metastasis, intraperitoneal (IP) chemotherapy can maintain a high drug concentration in the abdominal cavit...

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Bibliographic Details
Main Authors: Yumei Zhang, Shunli Wang, Xiaofan Duan, Xiaoxiao Xu, Yuan Gao, Jiuli Zhou, Xiaolin Xu, Jin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
ovarian cancer
peritoneal metastasis
DTX-mPEG-PDLLA micelles
intraperitoneal administration
pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.861938/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.861938/full

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